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Ivermectin
IVM
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V.D
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0
0.25
0.5
0.75
1
1.25
1.5
1.75
2+
Gautret
0.34
[0.17-0.68]
2.4g
viral-
36
RR
CI
Dose (4d)
N
Huang (RCT)
0.08
[0.01-1.32]
4.0g (c)
recovery
22
Esper
0.36
[0.15-0.87]
2.0g
hospitalization
636
Ashraf
0.32
[0.10-1.10]
1.6g
death
82
Huang (ES)
0.41
[0.26-0.66]
2.0g (c)
viral-
69
Guérin
0.39
[0.02-9.06]
2.4g
death
54
Chen (RCT)
0.28
[0.10-0.82]
1.6g
viral-
30
Lagier
0.41
[0.27-0.62]
2.4g
death
3,737
Derwand
0.21
[0.03-1.47]
1.6g
death
518
Mitjà (RCT)
0.84
[0.35-2.03]
2.0g
hospitalization
293
Skipper (RCT)
0.48
[0.17-1.39]
3.2g
hospitalization
395
Hong
0.35
[0.13-0.72]
n/a
viral-
90
Bernabeu-Wittel
0.41
[0.36-0.95]
2.0g
death
272
Yu (ES)
0.15
[0.02-1.05]
1.6g
death
2,677
Ly
0.44
[0.26-0.75]
2.4g
death
226
Ip
0.45
[0.11-1.85]
n/a
death
1,067
Heras
0.04
[0.02-0.09]
n/a
death
100
Kirenga
0.74
[0.37-1.48]
n/a
recovery
56
Sulaiman
0.36
[0.17-0.80]
2.0g
death
5,541
Guisado-Vasco (ES)
0.33
[0.05-1.55]
n/a
death
607
Fonseca
0.36
[0.20-0.67]
2.0g
hospitalization
717
Cadegiani
0.19
[0.01-3.88]
1.6g
death
296
Simova
0.06
[0.00-1.13]
2.4g
hospitalization
38
Omrani (RCT)
0.88
[0.26-2.94]
2.4g
hospitalization
456
Agusti
0.32
[0.06-1.67]
2.0g
progression
142
Su
0.15
[0.04-0.57]
1.6g
progression
616
Amaravadi (DB RCT)
0.40
[0.13-1.28]
3.2g
recovery
27
Roy
0.98
[0.45-2.20]
n/a
recovery
29
Mokhtari
0.30
[0.20-0.45]
2.0g
death
28,759
Early treatment
0.35
[0.25-0.50]
44,235 patients
65% improvement
All 29 hydroxychloroquine COVID-19 early treatment studies
hcqmeta.com 4/14/21
Tau​
2
​
= 0.57; I​
2
​
= 87.8%; Z = 5.93 (p < 0.0001)
Lower Risk
Increased Risk
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0
0.25
0.5
0.75
1
1.25
1.5
1.75
2+
All studies
Early treatment
Effects reported
in all COVID-19
hydroxychloroquine studies
min, Q1, median, Q3, max
Lower Risk
Increased Risk
hcqmeta.com 4/14/21
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