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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Mortality 17% Improvement Relative Risk Death/intubation -75% c19hcq.com Abdulrahman et al. HCQ for COVID-19 LATE TREATMENT Favors HCQ Favors control
Abdulrahman, 446 patient HCQ late treatment PSM study: 17% lower mortality [p=1] and 75% higher combined mortality/intubation [p=0.24] https://c19p.org/abdulrahman
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The efficacy and safety of hydroxychloroquine in COVID19 patients : a multicenter national retrospective cohort
Abdulrahman et al., medRxiv, doi:10.1101/2020.11.25.20234914 (Preprint)
30 Nov 2020    Source   PDF   Share   Tweet
Retrospective medical record analysis of acute care patients in Bahrain not showing a significant effect of HCQ.
Confounding by indication is likely. Matching appears not to have matched for baseline severity - 17.5% of HCQ patients required oxygen while only 12.6% of control patients did.
risk of death, 16.7% lower, RR 0.83, p = 1.00, treatment 5 of 223 (2.2%), control 6 of 223 (2.7%), NNT 223, PSM.
risk of death/intubation, 75.0% higher, RR 1.75, p = 0.24, treatment 12 of 223 (5.4%), control 7 of 223 (3.1%), adjusted per study, PSM.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Abdulrahman et al., 11/30/2020, retrospective, propensity score matching, Bahrain, Middle East, preprint, 9 authors.
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Late treatment
is less effective
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