et al., Kidney Int., 98:1, 20-26, July 1, 2020, doi:10.1016/j.kint.2020.04.030 (preprint 5/10) (Peer Reviewed)
Analysis of 94 hemodialysis COVID-19 positive patients. Reduction in death seen with HCQ but p
=0.12, OR 0.44 [0.16–1.24].
Alberici et al., 5/10/2020, retrospective, Italy, Europe, peer-reviewed, 31 authors.
risk of death, 42.9% lower, RR 0.57, p = 0.12, treatment 17 of 72 (23.6%), control 9 of 22 (40.9%), odds ratio converted to relative risk.
Effect extraction follows pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.