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0 0.5 1 1.5 2+ Mortality -7% Improvement Relative Risk c19hcq.com Alghamdi et al. HCQ for COVID-19 LATE TREATMENT Favors HCQ Favors control
Alghamdi, 775 patient HCQ late treatment study: 7% higher mortality [p=0.88] https://c19p.org/alghamdi
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Clinical Efficacy of Hydroxychloroquine in Patients with COVID-19: Findings from an Observational Comparative Study in Saudi Arabia
Alghamdi et al., Antibiotics, doi:10.3390/antibiotics10040365
31 Mar 2021    Source   PDF   Share   Tweet
Retrospective 775 hospitalized patients in Saudi Arabia showing no significant difference. There was no adjustment for severity or comorbidities. Confounding by indication is likely.
risk of death, 6.9% higher, RR 1.07, p = 0.88, treatment 44 of 568 (7.7%), control 15 of 207 (7.2%).
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: confounding by indication is likely and adjustments do not consider COVID-19 severity at baseline.
Alghamdi et al., 3/31/2021, retrospective, Saudi Arabia, Middle East, peer-reviewed, 10 authors.
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is less effective
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