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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Mortality -7% Improvement Relative Risk c19hcq.com/alghamdi.html Favors HCQ Favors control
31 March 2021 - Late treatment study
Clinical Efficacy of Hydroxychloroquine in Patients with COVID-19: Findings from an Observational Comparative Study in Saudi Arabia
Alghamdi et al., Antibiotics, doi:10.3390/antibiotics10040365 (Peer Reviewed)
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Retrospective 775 hospitalized patients in Saudi Arabia showing no significant difference. There was no adjustment for severity or comorbidities. Confounding by indication is likely.
risk of death, 6.9% higher, RR 1.07, p = 0.88, treatment 44 of 568 (7.7%), control 15 of 207 (7.2%).
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
This study is excluded in the after exclusion results of meta analysis: confounding by indication is likely and adjustments do not consider COVID-19 severity.
Alghamdi et al., 3/31/2021, retrospective, Saudi Arabia, Middle East, peer-reviewed, 10 authors.
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