Retrospective 171 ICU patients in Saudi Arabia showing no significant difference for HCQ treatment in unadjusted results.
Alghamdi et al., 8/4/2021, retrospective, Saudi Arabia, Middle East, peer-reviewed, 1 author.
risk of death, 39.2% higher, RR 1.39, p = 0.52, treatment 29 of 128 (22.7%), control 7 of 43 (16.3%).
This study is excluded in the after exclusion results of meta analysis: unadjusted results with no group details, very late stage, ICU patients.
Effect extraction follows pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.