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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Mortality -134% Improvement Relative Risk c19hcq.com/alotaibi.html Favors HCQ Favors favipiravir
14 September 2021 - Late treatment study
Effectiveness and Safety of Favipiravir Compared to Hydroxychloroquine for Management of Covid-19: A Retrospective Study
Alotaibi et al., International Journal of General Medicine, 2021:14 (Peer Reviewed)
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Retrospective hospitalized patients in Saudi Arabia, showing lower mortality with favipiravir compared to HCQ, not quite reaching statistical significance. Authors do not indicate the factors behind which therapy was chosen. Confounding by indication and time are possible.
risk of death, 133.5% higher, RR 2.33, p = 0.05, treatment 193, control 244, multivariate.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
Alotaibi et al., 9/14/2021, retrospective, Saudi Arabia, Middle East, peer-reviewed, 11 authors, this trial compares with another treatment - results may be better when compared to placebo.
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