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0 0.5 1 1.5 2+ Mortality 59% Improvement Relative Risk Ventilation 81% Severe case 33% c19hcq.com Alzahrani et al. HCQ for COVID-19 PrEP Favors HCQ Favors control
Alzahrani, 47 patient HCQ prophylaxis study: 59% lower mortality [p=1], 81% lower ventilation [p=0.54], and 33% lower severe cases [p=0.7] https://c19p.org/alzahrani
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Clinical characteristics and outcome of COVID-19 in patients with rheumatic diseases
Alzahrani et al., Rheumatology International , doi:10.1007/s00296-021-04857-9
15 Apr 2021    Source   PDF   Share   Tweet
Retrospective 47 rheumatic disease patients not finding significant differences with HCQ.
risk of death, 58.7% lower, RR 0.41, p = 1.00, treatment 0 of 14 (0.0%), control 1 of 33 (3.0%), NNT 33, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm).
risk of mechanical ventilation, 81.0% lower, RR 0.19, p = 0.54, treatment 0 of 14 (0.0%), control 3 of 33 (9.1%), NNT 11, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm).
risk of severe case, 32.7% lower, RR 0.67, p = 0.70, treatment 2 of 14 (14.3%), control 7 of 33 (21.2%), NNT 14.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Alzahrani et al., 4/15/2021, retrospective, Saudi Arabia, Middle East, peer-reviewed, 3 authors.
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