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0 0.5 1 1.5 2+ Mortality 68% Improvement Relative Risk c19hcq.com Ashraf et al. HCQ for COVID-19 EARLY TREATMENT Favors HCQ Favors control
Ashraf, 100 patient HCQ early treatment study: 68% lower mortality [p=0.15] https://c19p.org/ashraf
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COVID-19 in Iran, a comprehensive investigation from exposure to treatment outcomes
Ashraf et al., medRxiv doi:10.1101/2020.04.20.20072421.t (Preprint)
24 Apr 2020    Source   PDF   Share   Tweet
Small limited trial with 100 patients concluding that HCQ improved clinical outcome, OR 0.016 [0.002-0.11] in regression analysis.
risk of death, 67.5% lower, RR 0.32, p = 0.15, treatment 10 of 77 (13.0%), control 2 of 5 (40.0%), NNT 3.7.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Ashraf et al., 4/24/2020, retrospective, database analysis, Iran, Middle East, preprint, median age 58.0, 16 authors, dosage 200mg bid daily, 400mg qd was used when combined with Lopinavir-Ritonavir.
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