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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Mortality 41% Improvement Relative Risk Severe case 59% c19vitamind.com/atanasovska.html Favors vitamin D Favors control
2 November 2021 - Analysis of outcomes based on serum levels
Vitamin D levels and oxidative stress markers in patients hospitalized with COVID-19
Atanasovska et al., Redox Report, doi:10.1080/13510002.2021.1999126 (Peer Reviewed)
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Retrospective 33 COVID-19 hospitalized patients in North Macedonia, showing significantly lower vitamin D levels for severe vs. moderate cases. Oxidative stress was also higher for vitamin D insufficient patients.
risk of death, 40.7% lower, RR 0.59, p = 0.68, high D levels (≥30ng/mL) 2 of 9 (22.2%), low D levels (<30ng/mL) 9 of 24 (37.5%), NNT 6.5.
risk of severe case, 59.0% lower, RR 0.41, p = 0.13, high D levels (≥30ng/mL) 2 of 9 (22.2%), low D levels (<30ng/mL) 13 of 24 (54.2%), NNT 3.1.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
Atanasovska et al., 11/2/2021, retrospective, North Macedonia, Europe, peer-reviewed, 8 authors, average treatment delay 10.45 days.
Contact: marija.petrusevska@medf.ukim.edu.mk.
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