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0 0.5 1 1.5 2+ Mortality 52% Improvement Relative Risk c19hcq.com Ayerbe et al. HCQ for COVID-19 LATE TREATMENT Favors HCQ Favors control
Ayerbe, 2,075 patient HCQ late treatment study: 52% lower mortality [p=0.001] https://c19p.org/ayerbe
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The association of treatment with hydroxychloroquine and hospital mortality in COVID-19 patients
Ayerbe et al., Internal and Emergency Medicine, doi:0.1007/s11739-020-02505-x
30 Sep 2020    Source   PDF   Share   Tweet
2075 hospital patients in Spain showing HCQ reduces mortality 52%, odds ratio OR 0.39, p<0.001, after adjustment for age, gender, temperature > 37 °C, and saturation of oxygen < 90% treatment with azithromycin, steroids, heparin, tocilizumab, a combination of lopinavir with ritonavir, and oseltamivir, and date of admission (model 4).
risk of death, 52.2% lower, RR 0.48, p < 0.001, treatment 237 of 1,857 (12.8%), control 49 of 162 (30.2%), NNT 5.7, adjusted per study, odds ratio converted to relative risk.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Ayerbe et al., 9/30/2020, retrospective, database analysis, Spain, Europe, peer-reviewed, 3 authors.
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