COVID-19 in hospitalized patients in 4 hospitals in San Isidro, Buenos Aires, Argentina

7/31 Late treatment study

Barra et al., medRxiv, doi:10.1101/2021.07.30.21261220 (Preprint)
COVID-19 in hospitalized patients in 4 hospitals in San Isidro, Buenos Aires, Argentina

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Retrospective 668 hospitalized patients in Argentina, 18 treated with HCQ, not showing a significant difference in unadjusted results.

Barra et al., 7/31/2021, retrospective, Argentina, South America, preprint, 12 authors.

risk of death, 10.8% lower, RR 0.89, p = 1.00, treatment 2 of 18 (11.1%), control 81 of 650 (12.5%), unadjusted.

This study is excluded in meta analysis: unadjusted results with no group details.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.

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