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0 0.5 1 1.5 2+ Mortality -120% Improvement Relative Risk c19hcq.com Barrat-Due et al. NCT04321616 HCQ RCT LATE TREATMENT Favors HCQ Favors control
Barrat-Due, 93 patient HCQ late treatment RCT: 120% higher mortality [p=0.35] https://c19p.org/barratdue
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Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19
Barrat-Due et al., Annals of Internal Medicine, doi:10.7326/M21-0653
13 Jul 2021    Source   PDF   Share   Tweet
Small RCT in Norway with 52 HCQ and 42 remdesivir patients, showing no significant differences with treatment. Add-on trial to WHO Solidarity. NCT04321616.
risk of death, 120.0% higher, RR 2.20, p = 0.35, treatment 4 of 45 (8.9%), control 2 of 48 (4.2%), adjusted per study.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Barrat-Due et al., 7/13/2021, Double Blind Randomized Controlled Trial, Norway, Europe, peer-reviewed, 41 authors, average treatment delay 8.0 days, trial NCT04321616.
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This PaperHCQAll
Late treatment
is less effective
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