605 hospitalized patients in Saudi Arabia showing no mortality with HCQ (only 6 patients received HCQ).
Barry et al., 3/23/2021, retrospective, Saudi Arabia, Middle East, peer-reviewed, 14 authors.
risk of death, 98.9% lower, RR 0.01, p = 0.60, treatment 0 of 6 (0.0%), control 91 of 599 (15.2%), continuity correction due to zero event (with reciprocal of the contrasting arm).
Effect extraction follows pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.