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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Mechanical ventilation 40% Improvement Relative Risk c19hcq.com/capsoni.html Favors HCQ Favors control
1 December 2020 - Late treatment study
CPAP Treatment In COVID-19 Patients: A Retrospective Observational Study In The Emergency Department
Capsoni et al., Research Square, doi:10.21203/rs.3.rs-113418/v1 (Preprint)
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Small 52 patient retrospective study of patients with acute respiratory failure showing lower rates of intubation with HCQ.
risk of mechanical ventilation, 40.0% lower, RR 0.60, p = 0.30, treatment 12 of 40 (30.0%), control 6 of 12 (50.0%), NNT 5.0.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
Capsoni et al., 12/1/2020, retrospective, Italy, Europe, preprint, 13 authors, average treatment delay 7.0 days.
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