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0 0.5 1 1.5 2+ Hospitalization 95% Improvement Relative Risk c19hcq.com Chechter et al. HCQ for COVID-19 EARLY TREATMENT Favors HCQ Favors control
Chechter, 72 patient HCQ early treatment study: 95% lower hospitalization [p=0.004] https://c19p.org/chechter
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Evaluation of patients treated by telemedicine in the COVID-19 pandemic by a private clinic in Sao Paulo, Brazil: A non-randomized clinical trial preliminary study
Chechter et al., medRxiv, doi:10.1101/2021.11.05.21265569 (Preprint)
5 Nov 2021    Source   PDF   Share   Tweet
Prospective study of 187 telemedicine patients in Brazil. 74 presenting with moderate symptoms were offered treatment with HCQ+AZ, 12 did not accept HCQ (taking AZ only), forming a control group. There was lower hospitalization and improved recovery with treatment. There appears to be different group sizes in the text and tables without explanation (maybe a typo). RBR-658khm.
risk of hospitalization, 94.7% lower, RR 0.05, p = 0.004, treatment 0 of 60 (0.0%), control 3 of 12 (25.0%), NNT 4.0, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm).
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: unadjusted results with no group details.
Chechter et al., 11/5/2021, prospective, Brazil, South America, preprint, 13 authors, dosage 800mg day 1, 400mg days 2-5, this trial uses multiple treatments in the treatment arm (combined with AZ) - results of individual treatments may vary.
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