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0 0.5 1 1.5 2+ Median time to PCR- 72% Improvement Relative Risk c19hcq.com Chen et al. HCQ for COVID-19 RCT EARLY TREATMENT Favors HCQ Favors control
Chen, 48 patient HCQ early treatment RCT: 72% faster viral clearance [p=0.01] https://c19p.org/chen
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Efficacy and safety of chloroquine or hydroxychloroquine in moderate type of COVID-19: a prospective open-label randomized controlled study
Chen et al., medRxiv, doi:10.1101/2020.06.19.20136093 (Preprint)
22 Jun 2020    Source   PDF   Share   Tweet
Significantly faster clinical recovery and shorter time to RNA negative (from 7.0 days to 2.0 days (HCQ), p=0.01. 67 patients with mild/moderate cases.
median time to PCR-, 72.0% lower, relative time 0.28, p = 0.01, treatment 18, control 12.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Chen et al., 6/22/2020, Randomized Controlled Trial, China, Asia, preprint, 19 authors, dosage 200mg bid days 1-10.
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