et al., American Journal of Transplantation, doi:10.1111/ajt.16185 (Peer Reviewed)
Analysis of 144 hospitalized kidney transplant patients showing HCQ mortality HR 1.53, p
= 0.17. Subject to confounding by indication.
Cravedi et al., 7/10/2020, retrospective, USA, multiple countries, North America, multiple regions, peer-reviewed, mean age 60.0, 25 authors.
risk of death, 53.0% higher, RR 1.53, p = 0.17, treatment 36 of 101 (35.6%), control 10 of 43 (23.3%).
Effect extraction follows pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.