Cravedi et al., American Journal of Transplantation,
doi:10.1111/ajt.16185 (Peer Reviewed)
COVID‐19 and kidney transplantation: Results from the TANGO International Transplant Consortium
Analysis of 144 hospitalized kidney transplant patients showing HCQ mortality HR 1.53,
p = 0.17. Subject to confounding by indication.
Cravedi et al., 7/10/2020, retrospective, USA, North America, peer-reviewed, mean age 60.0, 25 authors.
risk of death, 53.0% higher, RR 1.53, p = 0.17, treatment 36 of 101 (35.6%), control 10 of 43 (23.3%).
This study is excluded in meta analysis: substantial unadjusted confounding by indication likely.
Effect extraction follows
pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.