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0 0.5 1 1.5 2+ Mortality -105% Improvement Relative Risk c19hcq.com De Luna et al. HCQ for COVID-19 LATE TREATMENT Favors HCQ Favors control
De Luna, 150 patient HCQ late treatment study: 105% higher mortality [p=0.69] https://c19p.org/deluna
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Clinical and Demographic Characteristics of COVID-19 Patients Admitted in a Tertiary Care Hospital in the Dominican Republic
De Luna et al., medRxiv, doi:10.1101/2020.12.11.20247437 (Preprint)
14 Dec 2020    Source   PDF   Share   Tweet
Retrospective 150 patients in the Dominican Republic, 132 treated with HCQ, showing higher mortality with treatment in unadjusted results. Confounding by indication is likely.
risk of death, 104.5% higher, RR 2.05, p = 0.69, treatment 15 of 132 (11.4%), control 1 of 18 (5.6%).
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: unadjusted results with no group details, substantial unadjusted confounding by indication likely.
De Luna et al., 12/14/2020, retrospective, Dominican Republic, Caribbean, preprint, 10 authors.
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Late treatment
is less effective
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