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0 0.5 1 1.5 2+ ICU admission 88% Improvement Relative Risk c19hcq.com Dubernet et al. HCQ for COVID-19 LATE TREATMENT Favors HCQ Favors control
Dubernet, 36 patient HCQ late treatment study: 88% lower ICU admission [p=0.008] https://c19p.org/dubernet
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A comprehensive strategy for the early treatment of COVID-19 with azithromycin/hydroxychloroquine and/or corticosteroids: results of a retrospective observational study in the French overseas department of Reunion Island
Dubernet et al., J. Global Antimicrobial Resistance, doi:10.1016/j.jgar.2020.08.001
20 Aug 2020    Source   PDF   Share   Tweet
Retrospective analysis of 36 hospitalized patients showing HCQ/AZ associated with lower ICU admission, p=0.008. Median age 66, no mortality. Confounding by indication, however it was patients with hypoxemic pneumonia that were treated with HCQ/AZ, patients were not treated with HCQ/AZ if they didn't need oxygen therapy.
risk of ICU admission, 87.6% lower, RR 0.12, p = 0.008, treatment 1 of 17 (5.9%), control 9 of 19 (47.4%), NNT 2.4.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Dubernet et al., 8/20/2020, retrospective, France, Europe, peer-reviewed, median age 66.0, 20 authors.
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