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0 0.5 1 1.5 2+ Case 9% Improvement Relative Risk c19hcq.com Fitzgerald et al. HCQ for COVID-19 PrEP Favors HCQ Favors control
Fitzgerald, 4,666 patient HCQ prophylaxis study: 9% fewer cases [p=0.54] https://c19p.org/fitzgerald
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Risk Factors for Infection and Health Impacts of the COVID-19 Pandemic in People with Autoimmune Diseases
Fitzgerald et al., medRxiv, doi:10.1101/2021.02.03.21251069 (Preprint)
5 Feb 2021    Source   PDF   Share   Tweet
Retrospective 4666 people with autoimmune or inflammatory conditions, showing HCQ adjusted risk of COVID-19 OR 0.91 [0.68-1.23]. Results are not adjusted for the significantly different risk of COVID-19 depending on the type and severity of autoimmune or inflammatory condition.
risk of case, 8.5% lower, RR 0.91, p = 0.54, treatment 65 of 1,072 (6.1%), control 200 of 3,594 (5.6%), adjusted per study, odds ratio converted to relative risk.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: not fully adjusting for the baseline risk differences within systemic autoimmune patients.
Fitzgerald et al., 2/5/2021, retrospective, USA, North America, preprint, 34 authors.
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