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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Mortality 37% Improvement Relative Risk Mortality (b) 24% c19hcq.com Frontera et al. HCQ for COVID-19 LATE TREATMENT Favors HCQ Favors control
Frontera, 3,473 patient HCQ late treatment PSM study: 37% lower mortality [p=0.02] https://c19p.org/frontera
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Treatment with Zinc is Associated with Reduced In-Hospital Mortality Among COVID-19 Patients: A Multi-Center Cohort Study
Frontera et al., Research Square, doi:10.21203/rs.3.rs-94509/v1 (Preprint)
26 Oct 2020    Source   PDF   Share   Tweet
Retrospective 3,473 hospitalized patients showing lower mortality with HCQ+zinc.
risk of death, 37.0% lower, HR 0.63, p = 0.01, treatment 121 of 1,006 (12.0%), control 424 of 2,467 (17.2%), NNT 19, adjusted per study, PSM.
risk of death, 24.0% lower, HR 0.76, p = 0.02, treatment 121 of 1,006 (12.0%), control 424 of 2,467 (17.2%), NNT 19, adjusted per study, regression.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Frontera et al., 10/26/2020, retrospective, propensity score matching, USA, North America, preprint, median age 64.0, 14 authors, this trial uses multiple treatments in the treatment arm (combined with zinc) - results of individual treatments may vary.
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Late treatment
is less effective
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