Vitamin D Levels Are Reduced at the Time of Hospital Admission in Sicilian SARS-CoV-2-Positive Patients
et al., International Journal of Environmental Research and Public Health,
Retrospective 50 COVID-19 hospitalized patients in Italy with vitamin D levels measured on admission, and 100 matched control patients, showing significantly lower vitamin D levels in COVID-19 patients. Vitamin D levels were also lower in COVID-19 patients with severe cases, without reaching statistical significance (p = 0.08, details not provided).
risk of case, 79.3% lower, RR 0.21, p < 0.001, high D levels 27 of 50 (54.0%) cases,
85 of 100 (85.0%) controls, NNT 2.7, case control OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
Gaudio et al., 3/27/2021, retrospective, Italy, Europe, peer-reviewed, 6 authors.