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0 0.5 1 1.5 2+ Mortality -22% Improvement Relative Risk Mortality (b) -21% Ventilation -55% Ventilation (b) -33% c19hcq.com Gerlovin et al. HCQ for COVID-19 LATE TREATMENT Favors HCQ Favors control
Gerlovin, 1,199 patient HCQ late treatment study: 22% higher mortality [p=0.18] and 55% higher ventilation [p=0.02] https://c19p.org/gerlovin
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Pharmacoepidemiology, Machine Learning and COVID-19: An intent-to-treat analysis of hydroxychloroquine, with or without azithromycin, and COVID-19 outcomes amongst hospitalized US Veterans
Gerlovin et al., American Journal of Epidemiology, doi:10.1093/aje/kwab183
24 Jun 2021    Source   PDF   Share   Tweet
Retrospective 1,769 hospitalized patients in the USA showing no significant differences for HCQ, and higher intubation for HCQ+AZ.
risk of death, 22.0% higher, HR 1.22, p = 0.18, treatment 90 of 429 (21.0%), control 141 of 770 (18.3%), adjusted per study, HCQ+AZ.
risk of death, 21.0% higher, HR 1.21, p = 0.33, treatment 49 of 228 (21.5%), control 141 of 770 (18.3%), adjusted per study, HCQ.
risk of mechanical ventilation, 55.0% higher, HR 1.55, p = 0.02, treatment 64 of 429 (14.9%), control 69 of 770 (9.0%), adjusted per study, HCQ+AZ.
risk of mechanical ventilation, 33.0% higher, HR 1.33, p = 0.25, treatment 32 of 228 (14.0%), control 69 of 770 (9.0%), adjusted per study, HCQ.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Gerlovin et al., 6/24/2021, retrospective, USA, North America, peer-reviewed, 21 authors.
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