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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Mortality 35% Improvement Relative Risk c19hcq.com/guglielmetti.html Favors HCQ Favors control
9 December 2020 - Late treatment study
Severe COVID-19 pneumonia in Piacenza, Italy – a cohort study of the first pandemic wave
Guglielmetti et al., Journal of Infection and Public Health, doi:10.1016/j.jiph.2020.11.012 (Peer Reviewed)
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Retrospective 218 hospitalized patients in Italy showing non-statistically significant 35% lower mortality with HCQ, hazard ratio aHR 0.65 [0.33–1.30].
risk of death, 35.0% lower, RR 0.65, p = 0.22, treatment 181, control 37, adjusted per study, multivariable Cox.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
Guglielmetti et al., 12/9/2020, retrospective, Italy, Europe, peer-reviewed, 16 authors.
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