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HCQ study #141 of 320   Meta Analysis
9/12 Late treatment study
Heberto et al., IJC Heart & Vasculature, doi:10.1016/j.ijcha.2020.100638 (Peer Reviewed)
Implications of myocardial injury in Mexican hospitalized patients with coronavirus disease 2019 (COVID-19)
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Observational prospective 254 hospitalized patients, HCQ+AZ mortality odds ratio OR 0.36, p = 0.04.
Ventilation OR 0.20, p = 0.008.

Heberto et al., 9/12/2020, prospective, Mexico, North America, peer-reviewed, 8 authors.
risk of death, 53.6% lower, RR 0.46, p = 0.04, treatment 139, control 115, odds ratio converted to relative risk.
risk of mechanical ventilation, 65.6% lower, RR 0.34, p = 0.008, odds ratio converted to relative risk.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
All 320 studies   Meta Analysis
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