et al., IJC Heart & Vasculature, doi:10.1016/j.ijcha.2020.100638 (Peer Reviewed)
Observational prospective 254 hospitalized patients, HCQ+AZ mortality odds ratio OR 0.36, p
Ventilation OR 0.20, p
Heberto et al., 9/12/2020, prospective, Mexico, North America, peer-reviewed, 8 authors.
risk of death, 53.6% lower, RR 0.46, p = 0.04, treatment 139, control 115, odds ratio converted to relative risk.
risk of mechanical ventilation, 65.6% lower, RR 0.34, p = 0.008, odds ratio converted to relative risk.
Effect extraction follows pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.