Countries which Primarily Use Antimalarial Drugs As COVID-19 Treatment See Slower Dynamic of Daily Deaths

Izoulet M., SSRN, doi:10.2139/ssrn.3575899 (Preprint)
Countries which Primarily Use Antimalarial Drugs As COVID-19 Treatment See Slower Dynamic of Daily Deaths

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Compares the dynamics of daily deaths in the 10 days following the 3rd death in countries using and not using [H]CQ, showing dramatically lower death in [H]CQ countries. This paper does not attempt to account for population age and other differences between the countries and recommends further study.

Izoulet et al., 4/21/2020, retrospective, multiple countries, multiple regions, preprint, 1 author, dosage not specified.

risk of death, 85.0% lower, RR 0.15, p < 0.001.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.

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