Small retrospective database analysis of 36 patients receiving HCQ not showing significant differences. Confounding by indication is likely.
Kalligeros et al., 8/5/2020, retrospective, USA, North America, peer-reviewed, 13 authors.
risk of death, 67.0% higher, RR 1.67, p = 0.57, treatment 36, control 72.
Effect extraction follows pre-specified rules prioritizing more serious
outcomes. For an individual study the most serious outcome may have a smaller
number of events and lower statistical signficance, however this provides the
strongest evidence for the most serious outcomes when combining the results of
many trials.