Characteristics and outcomes of admitted patients infected with SARS-CoV-2 in Uganda

9/9 Early, Late

Kirenga et al., BMJ Open Respiratory Research, doi:10.1136/bmjresp-2020-000646 (Peer Reviewed)
Characteristics and outcomes of admitted patients infected with SARS-CoV-2 in Uganda

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Prospective 56 patients in Uganda, 29 HCQ and 27 control, showing 25.6% faster recovery with HCQ, 6.4 vs. 8.6 days (p = 0.20). There was no ICU admission, mechanical ventilation, or death.

Treatment delay is not specified but at least a portion of patients appear to have been treated early.

Kirenga et al., 9/9/2020, prospective, Uganda, Africa, peer-reviewed, 29 authors, dosage not specified.

median time to recovery, 25.6% lower, relative time 0.74, p = 0.20, treatment 29, control 27.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.

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