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0 0.5 1 1.5 2+ Mortality 59% Improvement Relative Risk c19hcq.com Lagier et al. HCQ for COVID-19 LATE TREATMENT Favors HCQ Favors control
Lagier, 3,737 patient HCQ late treatment study: 59% lower mortality [p=0.05] https://c19p.org/lagier
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Outcomes of 3,737 COVID-19 patients treated with hydroxychloroquine/azithromycin and other regimens in Marseille, France: A retrospective analysis
Lagier et al., Travel Med. Infect. Dis. 101791, Jun 25, 2020, doi:10.1016/j.tmaid.2020.101791
25 Jun 2020    Source   PDF   Share   Tweet
Early treatment leads to significantly better clinical outcome and faster viral load reduction. Matched sample mortality HR 0.41 p-value 0.048. Retrospective 3,737 patients. This study includes both outpatients and hospitalized patients.
risk of death, 59.0% lower, HR 0.41, p = 0.048, treatment 35 of 3,119 (1.1%), control 58 of 618 (9.4%), adjusted per study.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Lagier et al., 6/25/2020, retrospective, France, Europe, peer-reviewed, 22 authors, dosage 200mg tid days 1-10.
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Late treatment
is less effective
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