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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Mortality 32% Improvement Relative Risk c19hcq.com/lagier2.html Favors HCQ Favors control
4 June 2021 - Late treatment study
Outcomes of 2,111 COVID-19 hospitalised patients treated with 2 hydroxychloroquine/azithromycin and other regimens in Marseille, France: a 3 monocentric retrospective analysis
Lagier et al., Preprint (Preprint)
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Retrospective 2,011 hospitalized patients in France, median age 67, showing lower mortality with HCQ+AZ, and further benefit with the addition of zinc.
risk of death, 32.0% lower, RR 0.68, p = 0.004, treatment 93 of 1,270 (7.3%), control 146 of 841 (17.4%), NNT 10.0, adjusted per study, weighted multivariate Cox proportional hazards model.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
Lagier et al., 6/4/2021, retrospective, France, Europe, preprint, 32 authors.
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