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All Studies   Meta Analysis    Recent:   
0 0.5 1 1.5 2+ Mortality 50% Improvement Relative Risk HCQ for COVID-19  Lora-Tamayo et al.  LATE TREATMENT Is late treatment with HCQ beneficial for COVID-19? Retrospective 8,553 patients in Spain Lower mortality with HCQ (p<0.000001) c19hcq.org Lora-Tamayo et al., J. Infection, February 2021 Favors HCQ Favors control

Early Lopinavir/ritonavir does not reduce mortality in COVID-19 patients: results of a large multicenter study

Lora-Tamayo et al., J. Infection, doi:10.1016/j.jinf.2021.02.011
Feb 2021  
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HCQ for COVID-19
1st treatment shown to reduce risk in March 2020
 
*, now known with p < 0.00000000001 from 422 studies, recognized in 42 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
3,900+ studies for 60+ treatments. c19hcq.org
Lopinavir/ritonavir retrospective study also showing univariate results for HCQ, with significantly lower mortality.
risk of death, 50.5% lower, RR 0.50, p < 0.001, treatment 7,192, control 1,361, odds ratio converted to relative risk, univariate, control prevalence approximated with overall prevalence.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Lora-Tamayo et al., 11 Feb 2021, retrospective, Spain, peer-reviewed, 10 authors.
This PaperHCQAll
Short durations of corticosteroids for hospitalised COVID-19 patients are associated with a high readmission rate
Zain Chaudhry, Marianne Shawe-Taylor, Tommy Rampling, Tim Cutfield, Gabriella Bidwell, Xin Hui S Chan, Anna Last, Bryan Williams, Sarah Logan, Michael Marks, Hanif Esmail
Journal of Infection, doi:10.1016/j.jinf.2021.03.002
Oral corticoid, aspirin, anticoagulant, colchicine, and furosemide to improve the outcome of hospitalized COVID-19 patients -the COCAA-COLA cohort study Dear Editor,
Supplementary materials Supplementary material associated with this article can be found, in the online version, at doi:10.1016/j.jinf.2021.03.002 . Author contributions Haiyan Ethical statement Patient screening and case reviews were undertaken as part of routine infection control in the hospital. Ethics Ethical approval was not required for this service evaluation and audit of practice. Authors' contributions SD, AR and NM designed the study methodology. SD, TE and XG collated the data. SD drafted the initial manuscript with all authors contributing significantly to revising this for submission. All authors agreed on the final version for submission to the journal. Supplementary materials Supplementary material associated with this article can be found, in the online version, at doi:10.1016/j.jinf.2021.02.011 . Appendix List of the SEMI-COVID-19 network members Coordinator of the SEMI- COVID-19 Consent for publication All the authors agree to publish. Declaration of Competing Interest The authors declare that they have no competing interests. Declaration of Competing Interest The authors declare no conflict of interest Rapid whole-genome sequencing to inform COVID-19 outbreak response in Vietnam Dear Editor, The emergence of new SARS-CoV-2 variants, especially those of concerns, and their rapid dispersal emphasize the importance of active surveillance for SARS-CoV-2 variants worldwide. 1 , 2 In the morning of 28th January 2021, after 55 days..
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Late treatment
is less effective
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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