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Home   COVID-19 treatment studies for Vitamin D  COVID-19 treatment studies for Vitamin D  C19 studies: Vitamin D  Vitamin D   Select treatmentSelect treatmentTreatmentsTreatments
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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Mortality 33% Improvement Relative Risk Mortality (b) 27% Mortality (c) 25% Mortality (d) 12% c19vitamind.com/loucera.html Favors vitamin D Favors control
29 April 2021 - Prophylaxis study
Real world evidence of calcifediol or vitamin D prescription and mortality rate of COVID-19 in a retrospective cohort of hospitalized Andalusian patients
Loucera et al., Scientific Reports, doi:10.1038/s41598-021-02701-5 (preprint 4/29/21) (Peer Reviewed)
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Retrospective 15,968 hospitalized patients in Spain showing a significant reduction in mortality associated with the prescription of vitamin D, especially calcifediol, within 15-30 days prior to hospitalization.
risk of death, 33.0% lower, RR 0.67, p = 0.009, treatment 374, control 374, calcifediol, <15 days before hospitalization, Cox model with inverse propensity weighting.
risk of death, 27.0% lower, RR 0.73, p = 0.02, treatment 439, control 439, calcifediol, <30 days before hospitalization, Cox model with inverse propensity weighting.
risk of death, 25.0% lower, RR 0.75, p = 0.005, treatment 570, control 570, cholecalciferol, <15 days before hospitalization, Cox model with inverse propensity weighting.
risk of death, 12.0% lower, RR 0.88, p = 0.11, treatment 802, control 802, cholecalciferol, <30 days before hospitalization, Cox model with inverse propensity weighting.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
Loucera et al., 4/29/2021, retrospective, propensity score matching, Spain, Europe, peer-reviewed, 11 authors, dosage varies (calcifediol).
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