COVID-19 incidence and outcomes in a home dialysis unit in Madrid (Spain) at the height of the pandemic

11/5 Late treatment study

Maldonado et al., Nefrología, doi:10.1016/j.nefro.2020.09.002 (Peer Reviewed)
COVID-19 incidence and outcomes in a home dialysis unit in Madrid (Spain) at the height of the pandemic

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Very small retrospective of 12 dialysis patients showing 1/11 deaths with HCQ and 1/1 without HCQ.

Maldonado et al., 11/5/2020, retrospective, Spain, Europe, peer-reviewed, 10 authors.

risk of death, 90.9% lower, RR 0.09, p = 0.17, treatment 1 of 11 (9.1%), control 1 of 1 (100.0%).

This study is excluded in meta analysis: treatment or control group size extremely small.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.

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