11/5 Late treatment study
et al., Nefrología, doi:10.1016/j.nefro.2020.09.002 (Peer Reviewed)
COVID-19 incidence and outcomes in a home dialysis unit in Madrid (Spain) at the height of the pandemic
COVID-19 incidence and outcomes in a home dialysis unit in Madrid (Spain) at the height of the pandemic
Very small retrospective of 12 dialysis patients showing 1/11 deaths with HCQ and 1/1 without HCQ.
Maldonado et al., 11/5/2020, retrospective, Spain, Europe, peer-reviewed, 10 authors.
risk of death, 90.9% lower, RR 0.09, p = 0.17, treatment 1 of 11 (9.1%), control 1 of 1 (100.0%).
This study is excluded in the after exclusion results of meta analysis: treatment or control group size extremely small.
Effect extraction follows pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.
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