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0 0.5 1 1.5 2+ Case 90% Improvement Relative Risk Case (b) 88% c19hcq.com Mathai et al. HCQ for COVID-19 PrEP Favors HCQ Favors control
Mathai, 604 patient HCQ prophylaxis study: 90% fewer cases [p<0.0001] https://c19p.org/mathai
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Hydroxychloroquine as pre-exposure prophylaxis against COVID-19 in health-care workers: A single-center experience
Mathai et al., J. Marine Medical Society, doi:10.4103/jmms.jmms_115_20
6 Nov 2020    Source   PDF   Share   Tweet
90% reduction in cases with HCQ pre-exposure prophylaxis. Retrospective 604 healthcare workers.
risk of case, 89.5% lower, RR 0.10, p < 0.001, treatment 10 of 491 (2.0%), control 22 of 113 (19.5%), NNT 5.7.
risk of case, 88.5% lower, RR 0.12, p < 0.001, treatment 5 of 491 (1.0%), control 10 of 113 (8.8%), NNT 13, symptomatic.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Mathai et al., 11/6/2020, retrospective, India, South Asia, peer-reviewed, 3 authors.
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