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0 0.5 1 1.5 2+ Mortality 35% Improvement Relative Risk c19hcq.com Menardi et al. HCQ for COVID-19 LATE TREATMENT Favors HCQ Favors control
Menardi, 277 patient HCQ late treatment study: 35% lower mortality [p=0.12] https://c19p.org/menardi
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A retrospective analysis on pharmacological approaches to COVID-19 patients in an Italian hub hospital during the early phase of the pandemic
Menardi et al., PharmAdvances, doi:10.36118/pharmadvances.2021.15
30 Sep 2021    Source   PDF   Share   Tweet
Retrospective 277 hospitalized patients in Italy, showing lower mortality with HCQ treatment, not reaching statistical significance, and subject to confounding by indication.
risk of death, 35.2% lower, RR 0.65, p = 0.12, treatment 32 of 200 (16.0%), control 19 of 77 (24.7%), NNT 12.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: excessive unadjusted differences between groups, substantial unadjusted confounding by indication likely.
Menardi et al., 9/30/2021, retrospective, Italy, Europe, peer-reviewed, 10 authors.
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