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0 0.5 1 1.5 2+ Recovery time 29% Improvement Relative Risk Viral clearance -183% c19hcq.com Niwas et al. HCQ for COVID-19 LATE TREATMENT Favors HCQ Favors control
Niwas, 29 patient HCQ late treatment study: 29% faster recovery [p=0.008] https://c19p.org/niwas
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Clinical outcome, viral response and safety profile of chloroquine in COVID-19 patients — initial experience
Niwas et al., Advances in Respiratory Medicine, doi:10.5603/ARM.a2020.0139
1 Nov 2020    Source   PDF   Share   Tweet
Retrospective 12 hospitalized patients in India treated with CQ and 17 controls, showing faster recovery with treatment. There was no significant difference in viral clearance. The CQ group mean age was 41.3 vs. 47.6 for controls.
recovery time, 29.2% lower, relative time 0.71, p = 0.008, treatment mean 6.3 (±2.7) n=12, control mean 8.9 (±2.2) n=17.
risk of no viral clearance, 183.3% higher, RR 2.83, p = 0.55, treatment 2 of 12 (16.7%), control 1 of 17 (5.9%).
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: excessive unadjusted differences between groups.
Niwas et al., 11/1/2020, retrospective, India, South Asia, peer-reviewed, mean age 45.5, 17 authors.
Contact: rniwasaiims@gmail.com.
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