Clinical outcome, viral response and safety profile of chloroquine in COVID-19 patients — initial experience
et al., Advances in Respiratory Medicine,
Retrospective 12 hospitalized patients in India treated with CQ and 17 controls, showing faster recovery with treatment. There was no significant difference in viral clearance. The CQ group mean age was 41.3 vs. 47.6 for controls.
recovery time, 29.2% lower, relative time 0.71, p = 0.008, treatment mean 6.3 (±2.7) n=12, control mean 8.9 (±2.2) n=17.
risk of no viral clearance, 183.3% higher, RR 2.83, p = 0.55, treatment 2 of 12 (16.7%), control 1 of 17 (5.9%).
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta
excessive unadjusted differences between groups.
Niwas et al., 11/1/2020, retrospective, India, South Asia, peer-reviewed, mean age 45.5, 17 authors.