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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Mortality 8% Improvement Relative Risk c19hcq.com/nunezgill.html Favors HCQ Favors control
9 November 2020 - Late treatment study
Mortality risk assessment in Spain and Italy, insights of the HOPE COVID-19 registry
Núñez-Gil et al., Intern. Emerg. Med., doi:10.1007/s11739-020-02543-5 (Peer Reviewed)
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Retrospective database study of 1,021 patients in Ecuador, Germany, Italy, and Spain, showing HCQ propensity score adjusted mortality odds ratio aOR 0.88, p=0.005.
risk of death, 7.9% lower, RR 0.92, p = 0.005, treatment 200 of 686 (29.2%), control 100 of 268 (37.3%), NNT 12, adjusted per study, odds ratio converted to relative risk.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
Núñez-Gil et al., 11/9/2020, retrospective, database analysis, multiple countries, multiple regions, peer-reviewed, median age 68.0, 49 authors.
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