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0 0.5 1 1.5 2+ Hospitalization 45% Improvement Relative Risk c19hcq.com Opdam et al. HCQ for COVID-19 PrEP Favors HCQ Favors control
Opdam, 477 patient HCQ prophylaxis study: 45% lower hospitalization [p=0.18] https://c19p.org/opdam
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Identification of Risk Factors for COVID‐19 Hospitalization in Patients with Anti‐Rheumatic Drugs: Results from a Multicenter Nested Case Control Study
Opdam et al., Clinical Pharmacology & Therapeutics, doi:10.1002/cpt.2551
23 Feb 2022    Source   PDF   Share   Tweet
Retrospective 81 cases and 396 controls among rheumatic disease patients in the Netherlands, showing lower risk of hospitalization with HCQ prophylaxis, without statistical significance.
risk of hospitalization, 45.0% lower, OR 0.55, p = 0.18, treatment 8 of 81 (9.9%) cases, 59 of 396 (14.9%) controls, NNT 17, case control OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Opdam et al., 2/23/2022, retrospective, Netherlands, Europe, peer-reviewed, 9 authors.
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