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0 0.5 1 1.5 2+ Mortality 59% Improvement Relative Risk c19hcq.com Pinato et al. HCQ for COVID-19 LATE TREATMENT Favors HCQ Favors control
Pinato, 890 patient HCQ late treatment study: 59% lower mortality [p=0.0001] https://c19p.org/pinato
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Clinical portrait of the SARS-CoV-2 epidemic in European cancer patients
Pinato et al., Cancer Discovery, doi:10.1158/2159-8290.CD-20-0773
18 Aug 2020    Source   PDF   Share   Tweet
Restrospective 890 cancer patients with COVID-19, adjusted mortality HR for HCQ/CQ 0.41, p<0.0001.
Confirmed SARS-CoV-2 infection was required, which may help focus on more severe cases. Analysis with Cox proportional hazard model. Potential unmeasured confounders.
risk of death, 59.0% lower, HR 0.41, p < 0.001, treatment 30 of 182 (16.5%), control 181 of 446 (40.6%), NNT 4.1.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Pinato et al., 8/18/2020, retrospective, multiple countries, multiple regions, peer-reviewed, 64 authors.
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Late treatment
is less effective
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