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0 0.5 1 1.5 2+ Case 57% Improvement Relative Risk c19hcq.com Polat et al. HCQ for COVID-19 PEP Favors HCQ Favors control
Polat, 208 patient HCQ prophylaxis study: 57% fewer cases [p=0.03] https://c19p.org/polat
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Hydroxychloroquine Use on Healthcare Workers Exposed to COVID-19 - A Pandemic Hospital Experience
Polat et al., Medical Journal of Bakirkoy, 16:3, 280-6, doi:10.5222/BMJ.2020.50469
30 Sep 2020    Source   PDF   Share   Tweet
Small prophylaxis study of 208 healthcare workers in Turkey, 138 with high risk exposure received HCQ, while 70 with low and medium risk exposure did not. COVID-19 cases were lower in the treatment group, relative risk RR 0.43, p = 0.026. Since the control group had lower risk, the actual benefit may be larger.
risk of case, 57.0% lower, RR 0.43, p = 0.03, treatment 12 of 138 (8.7%), control 14 of 70 (20.0%), NNT 8.8.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Polat et al., 9/30/2020, prospective, Turkey, Europe, peer-reviewed, 3 authors.
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