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Home   COVID-19 treatment studies for Vitamin D  COVID-19 treatment studies for Vitamin D  C19 studies: Vitamin D  Vitamin D   Select treatmentSelect treatmentTreatmentsTreatments
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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Mortality 88% Improvement Relative Risk c19vitamind.com/ricci.html Favors vitamin D Favors control
3 March 2021 - Analysis of outcomes based on serum levels
Circulating Vitamin D levels status and clinical prognostic indices in COVID-19 patients
Ricci et al., Respiratory Research, doi:10.1186/s12931-021-01666-3 (Peer Reviewed)
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Retrospective 52 hospitalized COVID-19 patients showing that vitamin D deficiency is associated with compromised inflammatory responses and higher pulmonary involvement. Vitamin D deficient patients also showed higher mortality, although not quite reaching statistical significance with the small sample size.
risk of death, 87.6% lower, RR 0.12, p = 0.07, high D levels 0 of 30 (0.0%), low D levels 3 of 22 (13.6%), NNT 7.3, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm), >10 ng/mL.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
Ricci et al., 3/3/2021, retrospective, Italy, Europe, peer-reviewed, 15 authors.
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