Retrospective 17 hospitalized lung cancer patients showing lower mortality with HCQ+AZ treatment.
Rogado et al., 5/29/2020, retrospective, Spain, Europe, peer-reviewed, 9 authors.
risk of death, 91.6% lower, RR 0.08, p = 0.02, treatment 1 of 8 (12.5%), control 7 of 9 (77.8%), odds ratio converted to relative risk, multivariate logistic regression.
Effect extraction follows
pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.