Retrospective 79 hospitalized nonagenarian patients showing unadjusted HCQ mortality RR 0.84,
p = 0.76.
Roig et al., 1/31/2021, retrospective, Spain, Europe, peer-reviewed, 6 authors.
risk of death, 15.6% lower, RR 0.84, p = 0.76, treatment 33 of 67 (49.3%), control 7 of 12 (58.3%).
Effect extraction follows pre-specified rules prioritizing more serious
outcomes. For an individual study the most serious outcome may have a smaller
number of events and lower statistical signficance, however this provides the
strongest evidence for the most serious outcomes when combining the results of
many trials.