et al., Revista Espanola de Quimioterapia, doi:10.37201/req/130.2020 (Peer Reviewed)
Retrospective 79 hospitalized nonagenarian patients showing unadjusted HCQ mortality RR 0.84, p
Roig et al., 1/31/2021, retrospective, Spain, Europe, peer-reviewed, 6 authors.
risk of death, 15.6% lower, RR 0.84, p = 0.76, treatment 33 of 67 (49.3%), control 7 of 12 (58.3%).
Effect extraction follows pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.