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0 0.5 1 1.5 2+ Mortality 46% Improvement Relative Risk c19hcq.com Sánchez-Álvarez et al. HCQ for COVID-19 LATE Favors HCQ Favors control
Sánchez-Álvarez, 375 patient HCQ late treatment study: 46% lower mortality [p=0.005] https://c19p.org/sanchezalvarez
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Status of SARS-CoV-2 infection in patients on renal replacement therapy. Report of the COVID-19 Registry of the Spanish Society of Nephrology (SEN)
Sánchez-Álvarez et al., Nefrología, doi:10.1016/j.nefroe.2020.04.002
27 Apr 2020    Source   PDF   Share   Tweet
Analysis of 868 patients on renal replacement therapy. Statistically significant reduction in mortality with HCQ for patients on dialysis (OR 0.47, p=0.005).
No statistically significant change was found for transplant patients (the result is not given but likely the sample size is too small - the number of transplant patients was half the number of dialysis patients).
risk of death, 45.9% lower, RR 0.54, p = 0.005, treatment 322, control 53, odds ratio converted to relative risk.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Sánchez-Álvarez et al., 4/27/2020, retrospective, database analysis, Spain, Europe, peer-reviewed, mean age 67.0, 10 authors.
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Late treatment
is less effective
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