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COVID-19 in Individuals Treated With Long-Term Hydroxychloroquine: A Propensity Score-Matched Analysis of Cicatricial Alopecia Patients

Shaw et al., Journal of Drugs in Dermatology, doi:10.36849/JDD.5843

Jul 2021

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HCQ for COVID-19

1st treatment shown to reduce risk in March 2020

^*, now known with p < 0.00000000001 from 422 studies, recognized in 42 countries.

Lower risk for mortality, hospitalization, recovery, cases, and viral clearance.

No treatment is 100% effective. Protocols combine complementary and synergistic treatments. ^* >10% efficacy in meta analysis with ≥3 clinical studies.

4,000+ studies for 60+ treatments. c19hcq.org

PSM retrospective 144 alopecia patients in the USA, showing lower risk of COVID-19 with HCQ prophylaxis. The supplemental appendix is not available.

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risk of case, 13.0% lower, OR 0.87, p = 0.006, treatment 45, control 99, adjusted per study, propensity score matching, multivariable, RR approximated with OR.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates

Shaw et al., 1 Jul 2021, retrospective, USA, peer-reviewed, 10 authors, study period 1 March, 2020 - 15 May, 2020. Contact: Kristen.LoSicco@nyulangone.org.

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Abstract: doi:10.36849/JDD.5843 To order reprints or e-prints of JDD articles please contact sales@jddonline.com August 2021 914 Volume 20 • Issue 8 Copyright © 2021 LETTERS TO THE EDITOR Journal of Drugs in Dermatology COVID-19 in Individuals Treated With Long-Term Hydroxychloroquine: A Propensity Score-Matched Analysis of Cicatricial Alopecia Patients Katharina S. Shaw,a Lu Yin,a Jinal K. Shah,b Rachel A. Sally,a Katerina S. Svigos,a Prince U. Adotama,a Hsiao Han Tuan,a Jerry Shapiro MD,a Rebecca A. Betensky,b* and Kristen I. Lo Sicco MDa* The Ronald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York, NY b Department of Biostatistics, New York University School of Global Public Health, New York, NY a Both authors contributed equally to this work as co-first authors *

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