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HCQ study #146 of 264
9/24 Late treatment study
Shoaibi et al., medRxiv, doi:10.1101/2020.09.23.20199463 (Preprint)
Comparative Effectiveness of Famotidine in Hospitalized COVID-19 Patients
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Retrospective database analysis focused on Famotidine but also showing results for HCQ users, with unadjusted mortality RR 0.85, p<0.001 (13.6% vs. 16.1%).

Shoaibi et al., 9/24/2020, retrospective, database analysis, USA, North America, preprint, 5 authors.
risk of death, 15.4% lower, RR 0.85, p < 0.001, treatment 686 of 5047 (13.6%), control 3923 of 24404 (16.1%).

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
Details of all 264 studies    Meta analysis
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