Shousha, 547 patient HCQ late treatment study: 12% lower mortality [p=0.87] https://c19p.org/shoushah
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Hepatic and gastrointestinal disturbances in Egyptian patients infected with coronavirus disease 2019: A multicentre cohort study
et al., World Journal of Gastroenterology, doi:10.3748/wjg.v27.i40.6951
Retrospective 547 hospitalized COVID+ patients in Egypt, showing no significant differences with CQ/HCQ treatment in unadjusted analysis. Treatments were applied according to patient conditions, demographics, and comorbidities as per the the official guidelines, indicating strong confounding by indication.
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risk of death, 11.5% lower, RR 0.88, p = 0.87, treatment 12 of 136 (8.8%), control 41 of 411 (10.0%), NNT 87, unadjusted.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
This study is excluded in meta
analysis:
confounding by indication, unadjusted results and treatment used selectively per official protocol, unadjusted results with no group details.
Shousha et al., 28 Oct 2021, retrospective, Egypt, peer-reviewed, 18 authors, study period 15 April, 2020 - 29 July, 2020.
Late treatment
is less effective
is less effective
shousha
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