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0 0.5 1 1.5 2+ Mortality 47% Improvement Relative Risk c19hcq.com Signes-Costa et al. HCQ for COVID-19 LATE TREATMENT Favors HCQ Favors control
Signes-Costa, 5,847 patient HCQ late treatment study: 47% lower mortality [p=0.0005] https://c19p.org/signescosta
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Prevalence and 30-day mortality in hospitalized patients with COVID-19 and prior lung diseases
Signes-Costa et al., Archivos de Bronconeumología, doi:10.1016/j.arbres.2020.11.012
16 Dec 2020    Source   PDF   Share   Tweet
47% lower mortality with HCQ/CQ. Retrospective 1,271 patients with lung disease in Canada, China, Cuba, Ecuador, Germany, Italy and Spain, 83% treated with HCQ/CQ.
Multivariable Cox regression HCQ/CQ mortality hazard ratio HR 0.53, p < 0.001.
risk of death, 47.0% lower, RR 0.53, p < 0.001, treatment 4,854, control 993, adjusted per study.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Signes-Costa et al., 12/16/2020, retrospective, multiple countries, multiple regions, peer-reviewed, 28 authors.
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Late treatment
is less effective
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