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0 0.5 1 1.5 2+ Progression 85% Improvement Relative Risk Improvement time 24% Viral clearance 36% c19hcq.com Su et al. HCQ for COVID-19 EARLY TREATMENT Favors HCQ Favors control
Su, HCQ early treatment study: 85% lower progression [p=0.006], 24% faster improvement [p=0.02], and 36% improved viral clearance [p=0.001] https://c19p.org/su
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Efficacy of early hydroxychloroquine treatment in preventing COVID-19 pneumonia aggravation, the experience from Shanghai, China
Su et al., BioScience Trends, doi:10.5582/bst.2020.03340
23 Dec 2020    Source   PDF   Share   Tweet
85% lower disease progression with early use of HCQ. Retrospective 616 patients in China showing adjusted progression HR 0.15, p = 0.006.
risk of progression, 84.9% lower, HR 0.15, p = 0.006, adjusted per study, binary logistic regression.
improvement time, 24.0% better, relative time 0.76, p = 0.02, adjusted per study, Cox proportional hazards.
risk of no viral clearance, 35.8% lower, HR 0.64, p = 0.001, Cox proportional hazards.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Su et al., 12/23/2020, retrospective, China, Asia, peer-reviewed, 9 authors, study period 20 January, 2020 - 30 April, 2020, dosage 400mg days 1-10, 400mg daily for 10-14 days.
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