12/14 Late treatment study
et al., Virus Research, doi:10.1016/j.virusres.2020.198262 (Peer Reviewed)
A retrospective comparison of drugs against COVID-19
A retrospective comparison of drugs against COVID-19
Retrospective 333 patients in China, with only 8 HCQ patients, showing shorter duration of hospitalization with HCQ.
Tan et al., 12/14/2020, retrospective, China, Asia, peer-reviewed, 7 authors.
hospitalization time, 35.2% lower, relative time 0.65, p = 0.04, treatment 8, control 277.
Effect extraction follows pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.
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