Retrospective 333 patients in China, with only 8 HCQ patients, showing shorter duration of hospitalization with HCQ.
Tan et al., 12/14/2020, retrospective, China, Asia, peer-reviewed, 7 authors.
hospitalization time, 35.2% lower, relative time 0.65, p = 0.04, treatment 8, control 277.
Effect extraction follows pre-specified rules prioritizing more serious
outcomes. For an individual study the most serious outcome may have a smaller
number of events and lower statistical signficance, however this provides the
strongest evidence for the most serious outcomes when combining the results of
many trials.